EpiDentLatvia: Mapping the Epidemiological Profile of Oral Health in Latvian Children and Adolescents - id: RSU-ZG-2024/1-0044
Description: “RSU internal and RSU with LASE external consolidation” No. 5.2.1.1.i.0/2/24/I/CFLA/005
The EpiDentLatvia project targets the critical challenge of oral health in Latvia, where nearly all 12-year-olds have dental caries, exceeding the European average. Oral diseases, including dental caries, are among the most common non-communicable diseases worldwide, affecting children's school performance, future employment and economic productivity. The economic burden of oral health in Latvia is expected to increase significantly by 2040.
To address this, this project will use traditional statistics and machine learning to analyze data from our research group and national oral health datasets to compare the effectiveness of modern approaches. Our goals include identifying modifiable risk factors, predicting future demand for dental services, and mapping inequalities in access between different groups. This will support evidence-based policies, improve resource allocation and promote preventive dental care, in line with the WHO's agenda and the UN Sustainable Development Goals.
A central component of the project is its commitment to open science. It will shares all cleaned and anonymized datasets and analysis scripts in FAIR-compliant repositories, ensuring transparency and reproducibility and encouraging citizen science. This allows public participation and collaboration with policymakers. Our goal is to democratize research tools and foster collaboration in public health.
Identify Risk Factors for Early Childhood Caries: What risk factors and behaviors are linked to early childhood caries in Latvia, and what is the benefit of machine learning in helping to identify vulnerable populations?
Quantifying the Impact of Early Childhood Caries: How does early childhood caries affect general anesthesia use for dental treatments in Latvia? Can predictive models identify high-risk patients? Is it possible to identify patients at risk of GA re-interventions?
Evaluate the Accessibility of Dental Services: How accessible are dental services in Latvia, and what disparities exist in service availability?
Assessing Long-Term Effects of Dental Service Disruptions: What long-term effects did COVID-19 dental service disruptions have on preventive and non-invasive treatments in Latvia? What is the effect of limiting public dental care on the community?
Epidemiology of Oral Health in Adolescents in Latvia: What is the oral health status of Latvian adolescents aged 12–15, and how do lifestyle and socioeconomic factors influence their oral health outcomes?
Identify Risk Factors for Early Childhood Caries:
Analyze risk factors and prevalence and compare the performance of machine learning (Random Forests, XGBoost, LightGBM) against traditional regression.
Use R (tidymodels) for analysis, with cross-validation for model performance
Aims to develop targeted preventive strategies to reduce early childhood caries (ECC) in Latvia.
Quantifying the Impact of Early Childhood Caries:
Assess the impact of ECC on general anesthesia use for surgical treatment, and explore the usefulness of machine learning for predictive analysis.
Explores the value of shifting towards minimally invasive interventions.
Evaluate the Accessibility of Dental Services:
Integrate GIS to map service availability and disparities across socioeconomic regions.
Use spatial data layers and dynamic dashboards to identify underserved regions.
Inform national oral health policies and optimize resource allocation.
Assessing Long-Term Effects of Dental Service Disruptions:
Evaluate long-term effects of COVID-19 dental service disruptions on coverage and demand.
Assess the shift towards preventive, non-invasive treatments (SciRep2024, BMC2021).
Utilize the natural experiment of service disruptions to evaluate systemic changes.
Epidemiology of Oral Health in Adolescents in Latvia:
Profile oral health status of adolescents aged 12–15, linking outcomes to lifestyle and socioeconomic factors.
Evaluate the effectiveness of childhood interventions and forecast adult oral health trends.
Offers a longitudinal perspective on early childhood caries risk factors and service accessibility.
Principal investigator: Prof Dr Sergio Uribe - LinkedIn
Public Health Expert: Dr Ilze Maldupa - LinkedIn
Uribe, S., & Maldupa, I. (2025). Research Data Management Plan (DMP) for EpiDentLatvia: Mapping the Epidemiological Profile of Oral Health in Latvian Children and Adolescents (Version 1). Zenodo. https://doi.org/10.5281/zenodo.15313345
Identify Risk Factors for Early Childhood Caries: (Dataset ECC [not published yet]).
Quantifying the Impact of Early Childhood Caries: (Dataset GA [https://doi.org/10.48510/FK2/LUUOMS]).
Evaluate the Accessibility of Dental Services: (Dataset COVERAGE [10.17605/OSF.IO/R9YA7]).
Assessing Long-Term Effects of Dental Service Disruptions: (Dataset COVID [not published yet]).
Epidemiology of Oral Health in Adolescents in Latvia: (Dataset YOUNG [not published yet]).
MEMTAB, Birmingham, UK, 29th May - 1st April 2025
1. PMID: 38773884
Maldupa I, Narbutaite J, Stanceviciene E, Viduskalne I, Kalnina J, Kronina L, Brinkmane A, Senakola E, Uribe SE.
Int J Dent Hyg. 2025 Feb;23(1):124-132. doi: 10.1111/idh.12827. Epub 2024 May 21.
Free PMC article.
2. PMID: 38582806
Maldupa I, Innes N, Viduskalne I, Brinkmane A, Senakola E, Krumina K, Uribe SE.
Sci Rep. 2024 Apr 7;14(1):8123. doi: 10.1038/s41598-024-58850-w.
Free PMC article. Clinical Trial.
3. PMID: 38024146
Foláyan MO, Ramos-Gomez F, Fatusi OA, Nabil N, Lyimo GV, Minja IK, Masumo RM, Mohamed N, Potgieter N, Matanhire C, Maposa P, Akino CR, Adeniyi A, Mohebbi SZ, Ellakany P, Chen J, Amalia R, Iandolo A, Peedikayil FC, Aravind A, Al-Batayneh OB, Khader YS, Al-Maweri SA, Sabbah W, Abeldaño Zuñiga RA, Vukovic A, Jovanovic J, Jafar RM, Maldupa I, Arheiam A, Mendes FM, Uribe SE, López Jordi MDC, Villena RS, Duangthip D, Sam-Agudu NA, El Tantawi M.
Front Oral Health. 2023 Oct 20;4:1211242. doi: 10.3389/froh.2023.1211242. eCollection 2023.
Free PMC article. Review.
4. PMID: 36096784
COVID-19 as an opportunity for minimally-invasive dentistry: a national cross-sectional survey.
Maldupa I, Slepcova O, Vidulskane I, Brinkmane A, Senakola E, Uribe SE.
BMC Oral Health. 2022 Sep 12;22(1):394. doi: 10.1186/s12903-022-02432-7.
Free PMC article.
5. PMID: 34024331
Caries Prevalence and Severity for 12-Year-Old Children in Latvia.
Maldupa I, Sopule A, Uribe SE, Brinkmane A, Senakola E.
Int Dent J. 2021 Jun;71(3):214-223. doi: 10.1111/idj.12627. Epub 2021 Jan 27.
Free PMC article.
6. PMID: 33735529
Uribe SE, Innes N, Maldupa I.
Int J Paediatr Dent. 2021 Nov;31(6):817-830. doi: 10.1111/ipd.12783. Epub 2021 Apr 30.
Free PMC article.
7. PMID: 31107140
A Century of Change towards Prevention and Minimal Intervention in Cariology.
Innes NPT, Chu CH, Fontana M, Lo ECM, Thomson WM, Uribe S, Heiland M, Jepsen S, Schwendicke F.
J Dent Res. 2019 Jun;98(6):611-617. doi: 10.1177/0022034519837252.
Sļepcova, O. (Project leader), Maldupa, I. (Supervisor) & E. Uribe, S. (Supervisor)
2/10/23 → 30/09/27
Project: PhD projects
Stāmere, U. (Project leader), Maldupa, I. (Supervisor) & E. Uribe, S. (Supervisor)
2/10/23 → 30/09/27
Project: PhD projects
Maldupa, I. (Project leader), E. Uribe, S. (Work package leader), Innes, N. (Leading expert), Marino, R. (Leading expert), Viduskalne, I. (Expert), Grišakova, J. (Expert), Stars, I. (Expert), Evans, D. (Expert), Stāmere, U. (Assistant (student)), Sļepcova, O. (Assistant (student)), Gostilo, D. (Assistant (student)), Protasa, N. (Assistant (student)) & Vagale, E. (Assistant (student))
1/01/23 → 31/12/25
Project: Fundamental and Applied Research Programme
For PURE protocols: "Other contribution – Other contribution" type with status "Published".